產(chǎn)品屬性：
產(chǎn)品名稱 | Tyr-α-CGRP (human) (trifluoroacetate salt) |
規(guī)格 | 500μg |
貨號 | EY-01Y9556 |
Cas No.: 124756-98-5
別名: N/A
化學(xué)名: N/A
分子式: C172H276N52O51S2?XCF3COOH
分子量: 3952.5
溶解度: Water: 1 mg/ml
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide . It binds to amylin receptors AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respectively). Tyr-α-CGRP also binds to and stimulates cAMP accumulation in rat L6 myocytes (IC50 = 4 nM; EC50 = 12 nM). It also binds to rat brain and spleen membrane preparations (IC50s = 0.2 and 0.5 nM, respectively), induces positive chronotropic and inotropic effects in isolated right and left guinea pig atria (EC50s = 282 and 74 nM, respectively), and inhibits the twitch response in rat vas deferens (EC50 = 1.9 nM).
特別提醒公司產(chǎn)品僅供科研使用
