產(chǎn)品屬性：
產(chǎn)品名稱(chēng) | trans-Urocanic Acid |
規(guī)格 | 1g、5g |
貨號(hào) | EY-01Y10360 |
Cas No.: 3465-72-3
別名: N/A
化學(xué)名: N/A
分子式: C6H6N2O2
分子量: 138.1
溶解度: DMF: 3 mg/ml,DMSO: 15 mg/ml,PBS (pH 7.2): 0.3 mg/ml
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
trans-Urocanic acid is a major epidermal chromophore for the immunosuppressive effects of UV radiation that is produced in mammalian stratum corneum by the action of histidine ammonialyase on L-histidine. It contributes to the acidification of the surface of the stratum corneum, and its function has been proposed as that of an endogenous sunscreen, endowing a low-level of protection (SPF ~ 1.5) against UV-induced DNA damage and excessive keratinocyte apoptosis. Upon UVB exposure, trans-urocanic acid is converted to the cis isomer, which is known to activate regulatory T cells.
特別提醒公司產(chǎn)品僅供科研使用
