產(chǎn)品屬性：
產(chǎn)品名稱 | TNF-α Antagonist |
規(guī)格 | 500μg、1mg、5mg |
貨號 | EY-01Y10320 |
Cas No.: 199999-60-5
別名: N/A
化學名: N/A
分子式: C58H71N11O15S2
分子量: 1226.4
溶解度: DMSO: 5 mg/ml,DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor. By blocking the TNF receptor ligand contact site, this peptide interferes with both activating receptor activator of NF-κB (RANK) and TNF-α's recruitment and activation of osteoclasts. TNF-α antagonist has been used to block bone resorption in the study of systemic bone loss in rheumatoid arthritis and inflammatory bone destruction.
特別提醒公司產(chǎn)品僅供科研使用
