產(chǎn)品屬性：
產(chǎn)品名稱 | TAS4464 hydrochloride |
規(guī)格 | 100mg、250mg、500mg |
貨號 | EY-01Y10928 |
Cas No.: 1848959-11-4
別名: N/A
化學(xué)名: N/A
分子式: C21H24ClFN6O6S
分子量: 542.97
溶解度: DMSO: 83.33 mg/mL (153.47 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM[1].IC50:0.955 nM (NAE)[1][1]. Yoshimura C, et al. TAS4464, a highly potent and selective inhibitor of NEDD8 activating enzyme, suppresses neddylation and shows antitumor activity in diverse cancer models. Mol Cancer Ther. 2019 May 15.
特別提醒公司產(chǎn)品僅供科研使用
