產(chǎn)品屬性：
產(chǎn)品名稱 | Fmoc-Ala-Glu-Asn-Lys-NH2 |
規(guī)格 | 5 mg、10 mg |
貨號 | EY-01Y12144 |
Cas No.: 220701-06-4
別名: N/A
化學(xué)名: N/A
分子式: C33H43N7O9
分子量: 681.74
溶解度: DMSO: 100 mg/mL (146.68 mM; ultrasonic and warming and heat to 80°C)
儲存條件: -20°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing[1].Fmoc-Ala-Glu-Asn-Lys-NH2 antagonizes APP processing by AEP, whereas other small molecular inhibitors and inactive peptide AEQK were without effect[1].[1]. Zhang Z, et al. Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease. Nat Commun. 2015;6:8762. Published 2015 Nov 9.
特別提醒公司產(chǎn)品僅供科研使用
