產(chǎn)品屬性：
產(chǎn)品名稱 | c-met-IN-1 |
規(guī)格 | 100mg、250mg、500mg |
貨號 | EY-01Y12836 |
Cas No.: 2084836-84-8
別名: N/A
化學(xué)名: N/A
分子式: C35H37FN6O5
分子量: 640.7
溶解度: Soluble in DMSO
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
c-met-IN-1 (compound 16) is a potent and selective c-Met inhibitor, with IC50 of 1.1 nM, with antitumor activity.[1].IC50: 1.1 nM (c-Met)[1]c-met-IN-1 (compound 16) exhibits high selectivity and remarkable cytotoxicity against HT-29, MKN-45 and A549 cells with IC50 values of 0.08 μM, 0.22 μM and 0.07 μM, respectively[1].[1]. Wang X, et al. Design, synthesis and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives as selective c-Met inhibitors. Bioorg Med Chem. 2017 Feb 1;25(3):886-896.
特別提醒公司產(chǎn)品僅供科研使用
