產(chǎn)品屬性：
產(chǎn)品名稱 | T 26c disodium salt |
規(guī)格 | 5 mg、25 mg |
貨號 | EY-01Y13789 |
Cas No.: 869298-22-6
別名: N/A
化學名: N/A
分子式: C24H19N3Na2O6S
分子量: 523.47
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Highly potent and selective MMP13 inhibitor (IC50 = 6.9 pM). Exhibits >2600-fold selectivity for MMP13 over related MMPs. Inhibits degradation of bovine nasal septum cartilage explants in vitro . Orally bioavailable.Nara et al (2014) Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1" binding site. Bioorg.Med.Chem. 22 5487 PMID:25192810
特別提醒公司產(chǎn)品僅供科研使用
