產(chǎn)品屬性：
產(chǎn)品名稱 | Pimonidazole hydrochloride |
規(guī)格 | Free Sample (0.1-0.5 mg)、5mg、10mM*1mL in Water、50mg、100mg、200mg、500mg |
貨號(hào) | EY-01Y15704 |
Cas No.: 70132-51-3
別名: N/A
化學(xué)名: N/A
分子式: C11H19ClN4O3
分子量: 290.75
溶解度: H2O: 5 mg/mL (17.20 mM; ultrasonic and warming and heat to 80°C)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor[1]. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia [2].[1]. Varia MA, et al. Pimonidazole: a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in cervical carcinoma. Gynecol Oncol. 1998 Nov;71(2):270-7.
[2]. Masaki Y, et al. Imaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-Nitroimidazole-Based Agent "Pimonidazole" in Hypoxia. PLoS One. 2016 Aug 31;11(8):e0161639.
特別提醒公司產(chǎn)品僅供科研使用
