產(chǎn)品屬性：
產(chǎn)品名稱 | SPT Imidazopyridine 1 |
規(guī)格 | 10 mg、50 mg |
貨號 | EY-01Y16591 |
Cas No.: 1933533-18-6
別名: N/A
化學名: N/A
分子式: C22H24N2O3
分子量: 364.44
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Potent serine palmitoyl transferase (SPT) inhibitor (IC50 = 5 nM). Dose-dependently inhibits incorporation of 14C-serine into ceramide. Reduces plasma ceramide levels in vivo. Also increases plasma HDL and reduces vLDL cholesterol levels in rats.Genin et al (2016) Imidazopyridine and pyrazolopiperidine derivatives as novel inhibitors of serine palmitoyl transferase. J.Med.Chem. 59 5904 PMID:27213958
特別提醒公司產(chǎn)品僅供科研使用
