產品屬性：
產品名稱 | Ursodeoxycholic Acid (sodium salt) |
規(guī)格 | 250mg、500mg、1g、5g |
貨號 | EY-01Y16887 |
Cas No.: 2898-95-5
別名: N/A
化學名: N/A
分子式: C24H39O4?Na
分子量: 414.6
溶解度: DMF: 5 mg/ml,DMSO: 10 mg/ml,Ethanol: 15 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Ursodeoxycholic acid (UDCA) is a secondary bile acid formed via epimerization of chenodeoxycholic acid . UDCA is also a metabolite of lithocholic acid in human liver microsomes. It inhibits taurocholic acid uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 μM. UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid or ethanol in primary rat hepatocytes. Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.
特別提醒公司產品僅供科研使用
