產(chǎn)品屬性：
產(chǎn)品名稱 | Thiocarlide |
規(guī)格 | 50mg、100mg、500mg、1g |
貨號 | EY-01Y17629 |
Cas No.: 910-86-1
別名: Isoxyl
化學(xué)名: N,N'-bis[4-(3-methylbutoxy)phenyl]-thiourea
分子式: C23H32N2O2S
分子量: 400.6
溶解度: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 1 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Thiocarlide (isoxyl) is a thiourea derivative that was used in the 1960s to successfully treat tuberculosis (TB). It has considerable antimycobacterial activity in vitro and is effective against multi-drug resistant strains of Mycobacterium tuberculosis in the range of 1-10 μg/ml. [1] [2] At concentrations of 10 μM, isoxyl inhibits the synthesis of M. bovis during six hours of exposure which is similar to isoniazid (INH) and ethionamide (ETH), two other predominant anti-tuberculosis drugs. Unlike INH and ETH, isoxyl also partially inhibits the synthesis of fatty acids. Isoxyl shows no acute toxicity against primary macrophage cell cultures as demonstrated by diminution of redox activity.[2]
特別提醒公司產(chǎn)品僅供科研使用
