產(chǎn)品屬性：
產(chǎn)品名稱(chēng) | Theaflavine-3,3'-digallate |
規(guī)格 | 5mg |
貨號(hào) | EY-01Y19550 |
Cas No.: 33377-72-9
別名: N/A
化學(xué)名: (2S,3S)-2-(8-((2R,3R)-5,7-dihydroxy-3-((3,4,5-trihydroxybenzoyl)oxy)chroman-2-yl)-3,4,6-trihydroxy-5-oxo-5H-benzo[7]annulen-1-yl)-5,7-dihydroxychroman-3-yl 3,4,5-trihydroxybenzoate
分子式: C43H32O20
分子量: 868.7
溶解度: Soluble in DMSO
儲(chǔ)存條件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
1. Theaflavin-3,3'-digallate is an inducer of oxidative stress and apoptosis. 2. A combination microbicide containing theaflavin-3,3'-digallate and lactic acid can reduce herpes simplex virus (HSV) transmission. 3. Theaflavin-3,3'-digallate may be useful chemoprevention agents for prostate cancer through suppressing the function of androgen and its receptor. 4. Theaflavin-3, 3'-digallate has strong antioxidant and antiangiogenic activities, it inhibits the tube formation of endothelial cells via decreased both MMP-2 and MMP-9 activities in vitro. 5. Theaflavin-3,3'-digallate may exert its anti-inflammatory and cancer chemopreventive actions by suppressing the activation of NFkappaB through inhibition of IkappaB kinase (IKK) activity.6. Theaflavin-3,3'-digallate is a potent AMP-activated protein kinase (AMPK) activator with anti-adiposity activity in adipocytes, suggesting its potential application in functional foods and nutraceuticals for obesity management. 7. Theaflavin-3,3'-digallate can repress osteoclastogenesis and prevent wear debris-induced osteolysis via suppression of ERK pathway, it is a promising candidate for the treatment of osteoclast-related osteolytic diseases, such as wear debris-induced peri-implant osteolysis (PIO).
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