產品屬性：
產品名稱 | WIN 66,306 |
規(guī)格 | 1mg、5mg |
貨號 | EY-01Y21151 |
Cas No.: 151928-32-4
別名: N/A
化學名: N/A
分子式: C41H52N8O9
分子量: 800.9
溶解度:
儲存條件: -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
WIN 66,306 is a cyclic heptapeptide antagonist of neurokinin-1 (NK1) and NK2 receptors originally isolated from A. flavipes.1 It binds to NK1 and NK2 receptors (Kis = 8 and 3.8 μM, respectively, for the human receptors) and inhibits contractions induced by substance P in isolated guinea pig ileum in a concentration-dependent manner.1.Barrow, C.J., Doleman, M.S., Bobko, M.A., et al.Structure determination, pharmacological evaluation, and structure-activity studies of a new cyclic peptide substance P antagonist containing the new amino acid 3-prenyl-β-hydroxytyrosine, isolated from Aspergillus flavipesJ. Med. Chem.37(3)356-363(1994)
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