產品屬性：
產品名稱 | Teleocidin A1 |
規(guī)格 | 1mg、5mg |
貨號 | EY-01Y21152 |
Cas No.: 70497-14-2
別名: Lyngbyatoxin A
化學名: (2S,5S)-9-[(1R)-1-ethenyl-1,5-dimethyl-4-hexen-1-yl]-1,2,4,5,6,8-hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonin-3-one
分子式: C27H39N3O2
分子量: 437.6
溶解度: DMF: Soluble, DMSO: Soluble, Ethanol: Soluble, Methanol: Soluble
儲存條件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Teleocidin A1, also known as lyngbyatoxin A, is a fungal metabolite that has been isolated from S. mediocidicus and is the R enantiomer of (S)-teleocidin A. [1] It acts as a tumor promoter, inducing ornithine decarboxylase activity in mouse skin, increasing adhesion of HL-60 human leukemia cells (ED50 = 7 ng/ml), and inducing tumor formation in 87% of mice after 30 weeks when administered at a dose of 3 μg twice per week. [2] Teleocidin A1 also increases the production of prostaglandins and the turnover of choline in HeLa cells when used at concentrations ranging from 6 to 20 ng/ml. [3] It is a substrate for the methyltransferase TleD in Streptomyces where it is converted to teleocidin B.[4]
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